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Ginkgo Biloba L.: Mental Health Benefits from the World’s Oldest Living Tree

Gingko – A Traditional Medicine The seeds and leaves of Ginkgo biloba are used in traditional medicines. The two main bioactive constituents present in a concentrated standardized extract of Ginkgo biloba are Flavonoid Glycosides (24%) and terpene lactones (6%), which may act in a complementary manner. These molecules act as antioxidants/free radical scavengers, enzyme inhibitors, and cation chelators (1). The therapeutic mechanisms of action of the Ginkgo leaf extract are suggested to be through its antioxidant, antiplatelet, anti-hypoxic, anti-edemic, Hemorheology, and microcirculatory actions. Studies conducted shows that there is a significant improvement in speed of information processing in the brain related to working memory. The bioactive constituents from the Ginkgo biloba have the potential to act as a ‘smart drug’ or nootropic agent to improve intelligence (3). Mechanism of Action The Ginkgo leaf extract has been reported to have the therapeutical role in neurodegenerative disease prevention and enhancing mental health (stress release and memory enhancing action) (2): Inhibit the formation of Aβ from β-amyloid precursor protein (APP), a crucial process in the pathogenesis of Alzheimer’s disease Inhibits ROS accumulation induced by Aβ (particularly flavonol quercetin) and also reduces neuron apoptosis, where apoptosis is considered to be one of the main causes for neurodegenerative diseases and thus help to relieve Alzheimer’s disease Improve cerebral blood flow by stimulating Norepinephrine secretion Anxiety syndromes such as stress, moods, and depression are becoming common in the modern world. Since mood and emotion are related to stress, the alleviating effects of Ginkgo leaf extract may result in improving mood, thus resulting in antidepressant activity Stress involves a rise in the levels of glucocorticoids, and a subsequent memory dysfunction, increased anxiety, decreased immunity, gastrointestinal tract disturbances, myocardial infarction, or effects such as increased vigilance Decrease the corticosteroid synthesis and subsequently the circulating levels of glucocorticoids The memory enhancing effects of Ginkgo leaf extract is through prevention of neuron degeneration Side effects A transient headache has been documented as a side effect. The use of GBE has not been associated with other severe side effects to date. The whole plant, seeds, and pulp are occasionally associated with severe allergic reactions. Patients taking aspirin should exercise caution when adding GBE therapy (1). References 1. Kleijnen J, Knipschild P. Ginkgo biloba. Lancet 1992; 340: 1136 2. Mahadevan, S., and Y. Park. “Multifaceted therapeutic benefits of Ginkgo biloba L.: Chemistry, efficacy, safety, and uses.” Journal of Food Science 73.1 (2008): R14-R19. 3. Stough, Con, et al. “Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants.” International Journal of Neuropsychopharmacology 4.2 (2001): 131-134.

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Baby Diaper Rash Symptoms, Causes & Treatment

Causes and Cure of Diaper rash The world of cute little munchies is a magical world. A smile on a baby’s face means the whole world for the mother. But motherhood is no easy job, specially if you are a new mother. The journey for the first timers is laden with challenges. Your baby won’t be able to tell you their problem. A mother therefore has to be on a constant watch. One of the most frequent problems faced by mothers is how to take care of a severe diaper rash. If we listen to our grannies then the best thing to do is to let the babies live freely without any diapers. However, that is highly impractical in our day to day lives. But at the same time, a wet diaper is a little too dangerous for the baby’s health. Not only there is a probability of getting a rash but the baby can easily catch cold. But even after a watchful care, chances are very high that the infant might develop rashes. The severity of the rashes can be guessed from its redness. Sometimes rashes can become so harsh as to become blisters and cause bleeding. Causes of Diaper Rash More often than not, a rash can be developed because of either of the two reasons; 1. A yeast infection: This occurs mostly because of negligence. Diapers need to be changed every four 4 to 5 hours. Moist and warm environment spurs the growth of yeast. 2. Newly formed resistance or allergy to a certain product: Food, medicine or products of daily use by the infant. It has been noticed that some infants are allergic to citrus fruits. Chemicals in certain products of daily use like soaps and lotion can break out in the form of rashes. Treatment of Diaper Rash Try a different brand: The first step would be try diapers of a different brand. The reason is that although the brand might be the same, chances are likely that the brand might have switched to a different raisin or perfume. Handle the area gently: Always remember to wash your hands before touching the sensitive area of your baby. Rather than rubbing on a wipe which will only irritate the skin more, it is advised to use a clean wet cloth and pat dry the area. Buttiezzz: After that an even sprinkling of a thin layer of Buttiezzz is recommended. Buttiezzz is zinc oxide 10g per 100g. Zinc oxide is not only very effective in treating diaper rashes but it is also very helpful in preventing one. It forms a moisture lock layer. However it is not suggested for deep wounds. Cornstarch: If a rash breaks out because of yeast infection, one can try using medicated/home use cornstarch every time a diaper is changed. Medical consultation is a must if the rash does not subside within 3 to 4 days. If the above mentioned treatments doesn’t work, give us a call at 971 50 412 6081. Propharma is renowned online pharmaceutical products suppliers in UAE. We have a range of medical products for children.

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Activated Charcoal: The Truth vs. The Claim

Activated Charcoal is commonly used for medicine-related problems involving the absorption of organic toxins before it can damage the entire body as well as air and water purifier. In 1550BC, it was considered as a powerful poison antidote and a detoxifier which up to date is being embraced by many people. Presently, other significant benefits of Activated Charcoal have been claimed such as body detoxifier, hangover reliever, teeth whitener, bad breath killer, and skin toner. These claims may sound convincing, but are these claims really applicable in the real life? Let us try to find out! Claim #1: Activated Charcoal is a body Detoxifier. The Truth: FACT! Lab tests have proven that Activate Charcoal can remove E. Coli, a large group of bacteria that is commonly settling in the intestines of both humans and animals. Also, it is used to stabilize drug overdose cases. However, to achieve desirable results, it has to be processed within a couple of hours according to a test made by the Annals of Emergency Medicine. Otherwise, most toxins will be soaked up by the body; hence Activated Charcoal will only absorb the lesser amount of the remaining toxins. Claim #2: Activated Charcoal as Hangover Reliever The Truth: False. ! Experiencing headache and nausea after drinking a large volume of alcohol is mainly because of a drug overdose. Yes, you read it right! ALCOHOL is a DRUG! Activated Charcoal is not designed to absorb alcohol due to its chemical structure. As a result, it will not be able to treat the symptoms of alcohol overdose as claimed by Dr. Michael Lynch, Medical Doctor of Pittsburgh Poison Center. Claim #3: Activated charcoal serves as Teeth Whitener The Truth: Perhaps. Speculations say that by brushing or by cleaning your teeth using Activated Charcoal, it will take away the stains coming from tea, wine, coffee, and other discoloring substances upon spitting out. Testimonials promise convincing results from subjective experiments. Conversely, up to date, there is still no universal evidence of these claims. Claim #4: Activated Charcoal is bad breathe KILLER The Truth: TRUE! According to a Clinical Biochemist study, Activated Charcoal can be used to cure an awful kind of bad breathe, named as Trimethylamine. On the other hand, Chronic Halitosis or Acute tuna-fish breath is another dental issue. Claim #5: Activated Charcoal is effective as skin toner The Truth: Maybe YES, maybe NO. Beauty products companies would easily persuade a typical consumer who wished to have fair-younger-looking skin. They convince people that by simply applying Activated Charcoal on your face, it can tone your skin thoroughly. Though, Dr. Kraige Kraffert, a well-known dermatologist, says that science has not yet gathered enough evidence of this hypothesis during his interview with New York Daily News. Generally, Activated Charcoal is necessary at work, at home, on the vacation… ANYWHERE! It helps in the cases of nonspecific diarrhea, food, and chemical poisoning and as well for the regulation of the food digestion and other beneficial uses. It guarantees NO FLATUENCE, NO GASSES, and NO CRAMPS. You can easily have it now! Call Propharma Medical Supplies, UAE at +971 2 673 4781 or send an email at [email protected] from Sundays to Thursdays, 8:00AM to 6:00PM. You can also have a look on our best products that we have. Our Customer Service Department will be pleased to serve you. Order now!!!

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Green Coffee Benefits: FACT or FICTION?

Do you love COFFEE? Are you becoming ‘COFFEE holic’? Does COFFEE affect your appetite? What is the new trend of COFFEE? What things you still do not know about COFFEE? COFFEE is said to be a universal drink because of its pleasing taste and soothing smell that no one could ever resist. For instance, one-third of all tap water in the U.S. and in Europe is mainly used for brewing coffee. 71% of Americans was recorded as their total caffeine consumption that follows their intake of sodas and tea. Nowadays, a new trend of Green Coffee is booming around the world, which intrigues many researchers to conduct further studies to prove Green Coffee’s healthful benefits compare to drinking roasted Coffee beans. Is this argument fact or fiction? Well, let us count the ways… GREEN COFFEE: Fat Burning Agent and Antioxidant Researchers have proven that Green Coffee reduces body weight, absorption of fat in our diet, and liver-stored fats by using lab animals. In addition, Green coffee improves the role of a fat burning hormone, Adiponectin. Moreover, it was proven to have the same potent antioxidants found in green tea and grapes seed oil fighting the risks of cancers. Hypertension Reduction In a lab test conducted for a month, Green Coffee that contains chlorogenic acid was proven to reduce the level of hypertension. Different studies using different brands of Green Coffee extract – also homemade extract – came up with the same results. Natural Remedy in fighting Heart disease Another study was conducted to prove that Green Coffee can be a Natural Remedy in fighting Heart disease. Because of its Chlorogenic Acid, it was found out that it can evidently improve cholesterol and triglyceride health problems, which triggers the risks of having heart disease. However, this animal lab study was not yet completed to human studies. If the outcomes happen to be comparable, Green Coffee extract could be a Natural Remedy in fighting Heart disease Slow Carbohydrate Absorption Investigations claiming that Green Coffee can postpone the ingesting of carbohydrates in the digestive tract have been concluded factual. As a result, it lowers blood sugar and fewer insulin spikes. Drinking Green Coffee extract is the same way of taking lower carb diet. Lose 1 Pound per Week Based on a human study, experimenting 30 overweight individuals for 12 weeks was conducted to test the relativity of Green Coffee intake to losing weight. Divided into 2 groups, Group A was instructed to drink regular instant coffee while Group B was asked to drink the mixture of instant coffee and 200mg Green coffee bean extract. Same groups were asked to continue their normal diet and daily activities. After the 12 weeks of observation, the experiment showed that Group A only lost less than 4 pounds, but the other group greatly lost almost 12 pounds in weight. The study concluded that by drinking Green Coffee extract, it can significantly reduce a pound per week. This means that if you eat a kilogram or 2.2 pounds of food daily adding 10 grams or 1/3 ounces of green coffee extract, within two weeks you will have suppressed the potential weight gain from that food by 35%. This is really noteworthy! What are you waiting for? Order now!!! Propharma Medical Supplies is a legal distributor of Green Coffee Plus and herbal medicinal products in the UAE. You can order online at to avail the best discount we could offer to you. You can also call us at +971 2 673 4781 or send an email to [email protected] for further details from Sundays to Thursdays, 8:00AM to 6:00PM. Our team will be glad to assist you! Order now!!!

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The Sunshine irony in the Middle East

Having more than 82% of sunshine all throughout the year in the Middle East, you might assume that people living there receive an abundant quantity of natural vitamin coming from the Sun in their system. Shockingly, the region recorded several of the highest rates of Vitamin D deficiency not only in the neighborhood countries but registered worldwide. In the present, the frequency of hypovitaminosis D is between 20-80% in different countries in the MENA region. FACT or MYTH about Vitamin D? Based on recent studies, several communities in the Middle East do not acquire adequate Sun, which sounds to be a MYTH for many since the region receives natural sunlight 300 days in a year. However, studies concluded the following reasons to explain the issue in cultural and scientific ways: Limited activities outside due to a scorch and dry climate in many regions Lack of government regulations for vitamin D enrichment of food Most of the people in the middle east have dark skin color causing the production of Vitamin D very slow in their systems Practices like extended breastfeeding without sufficient vitamin D supplementation, obesity, drinking tea and coffee constantly, etc. are all reasons that contribute to the scarcity. Is Vitamin D deficiency a BIG DEAL? A big YES! One of the major roles of Vitamin D in our system is to support calcium absorption as well as to sustain its levels in our circulatory system. No matter how much level of Calcium you are adding to your daily meals, without Vitamin D to your body will not take Calcium thus will not be absorbed by your bones. As a result, the absence of minerals like Calcium will lead the bones becoming thin and vulnerable at all times. In the long run, it promotes a higher risk of fractures, osteoporosis, and osteoarthritis. However, Vitamin D’s function is not only for calcium absorption. Researchers claim that it also plays an important role as a hormone in preventing the effects of a vast range of more serious diseases such as types of cancers and diabetes, Crohn’s disease, heart attacks, hip fractures, obesity, Alzheimer’s, and multiple sclerosis. It is also associated with some disorders like chronic fatigue, weakness, muscle cramps, muscle weakness, chronic colds, and flu. In some cases, the deficiency of Vitamin D can also affect you psychologically. Seasonal Affective Disorder (SAD), a mood disorder manifesting depressive symptoms, typically occurs during winter when there is little amount sunshine, and accompanies with the rapid drop in vitamin D levels in the body. Researchers have observed that SAD occurs when sudden change of Vitamin D levels in the body that may contribute to the production of “Serotonin”, also known as the “Happy Hormone”. Up to date, investigations are still ongoing to prove the hypothesis. In conclusion, Vitamin D deficiency can be considered as a major public health issue in many parts of the world including yours; hence, YES, it is a big deal to everyone. Key Points to REMEMBER Your Vitamin D Level depends on two factors: Vitamin D production in the skin under the influence of ultraviolet radiation from the sun, which naturally initiates the transformation of cholesterol in the skin to vitamin D. Vitamin D can be taken through our daily diet from naturally containing food, fortified food, or vitamin supplements. Remember, 90% of a person’s daily requirement comes naturally from the sunlight. For this reason, if sun exposure is not suggestible, vitamin D supplementation is highly recommendable. How to get Vitamin D Supplements? Propharma Medical Supplies is one of the leading distributors of Vitamin D2 and D3 in the United Arab Emirates. With their high-quality products, your Vitamin D deficiency issues mentioned above will be resolved right away. To be assisted, please call +971 2 673 4781 or send an email to [email protected] from Sundays to Thursdays, 8:00Am to 6:00PM.

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Osteoarthritis Symptoms: Do you feel it?

Do you feel any pain, stiffness, or swollen joints to your body? When? How often? Be cautious!!! Other people tend to ignore these “PAINS” because they think that these are just normal for them and simply accept as if they are already part of their daily living. But in reality, these inconveniences should be taken seriously. Having sore or stiff joints in your hips, knees, and lower back in the morning after resting, after an extended activity, or even after a period of time being inactive are the common symptoms of Osteoarthritis. These symptoms usually develop over a period of time, hence are not noticeable at first. This is one of the reasons why many of not well-informed patients suffering from Osteoarthritis for a long time still end up consulting their doctors on the last minute of pain when everything turns to a more serious medical case. Do you feel these SYMPTOMS? • Pain that is worse after an activity or until the end of the day • Limited range of movement or stiffness • Cracking sound when joint bends • Mild swelling around a joint Suffering from Osteoarthritis can cause the difficulty to perform daily tasks at work or even at home such as lifting light weight things, cleaning an area, reaching stuff on a shelf, climbing stairs, grasping and holding objects, driving your car, or even simply bending your arms to eat. If you are already suffering from these pains, how will you be able to perform more difficult and more laborious tasks? These prove an English saying, “The pain of the little finger is being felt by the whole body”. Many of us consider that Osteoarthritis is unavoidable as age increases, so they do not take actions to avert before it happens or they do not look for ways to handle the pain and to manage the medical problem. Are you one of them? How can OSTEOARTHRITIS trigger other serious health problems? Diabetes and Heart Disease Knee, hip, or finger pain may lead to a stagnant way of living that triggers weight gain and possible obesity. Being overweight or obese can lead to other medical issues like diabetes, heart disease and high blood pressure. Falls and Fractures Based on recent studies, 30% of people with Osteoarthritis are prone to falling and have 20% greater risk of having fractures than those people without Osteoarthritis due to an inactive lifestyle resulting to having weak muscles to control the entire body properly. As a result, they could not perform a task efficiently which leads to becoming unproductive. Do you wish to put an end to your sufferings? Our team who are professionally trained would be glad to help you ease the pain that you are suffering from Osteoarthritis with the best products we can recommend to you which are very accessible in the market; Also, to address further issues about Osteoarthritis. For more details, please call Propharma Medical Supplies at +971 2 673 4781 or send an email to [email protected], Sundays to Thursdays from 8:00AM to 6:00PM (UAE Time). We are looking forward to assisting you!

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